The idea in brief : Spring batch as a model for CRISPR Cas9
The analogy between Spring Batch and the CRISPR-Cas9 system is an innovative conceptual model proposed notably by Wadï Mami on ResearchGate This framework transposes the steps of software engineering to molecular biology to structure the understanding of the genome editing process. ResearchGate +1 Component matching The architecture of Spring Batch (Read-Process-Write) aligns with the key phases of CRISPR-Cas9: ItemReader / Genome Identification : In Spring Batch, this Reader extracts the data. In biology, this corresponds to exploring and identifying the target DNA sequence within the genome. ItemProcessor / RNA Design and Binding : This Processor transforms the data. Here, it models the design of the guide RNA (gRNA) and the binding of the Cas9 enzyme to the target. Algorithms such as Karp-Rabin or Levenshtein distance...